This report is aims towards the analysis of clinical research, the importance of stethoscope disinfection and evidenced based practice. Adopting all the research based on medical field is the right option to go for the further analysis. The main reason for questionnaire is to design the research based literature for the same. Searching the appropriate literature before writing the final report is must. For that the electronic database can be used to get the relevant literature. The searching strategy can be changed in many ways and it depends on the type of article or subject. If the literature belongs to humanities or other science the search can be done on the relevant database. PICO method is used to analyses or prepares the correct format for clinical based questions. Evidence based health care practices are very important in deciding or analyzing the current medical technologies. This will use the previous research analysis in the medical and nursing areas. The aim of the report is to discuss the evidence based practices and analysis of the research design to perform the final action.