Combining Microfluidic and Lab- on- a- Chip Devices for automation and enhanced control
Lab on a chip is referred to as the device and method used to control and manipulates the flows of fluid at the levels of micro. These devices of microfluidic are known to manipulate and control the fluids in devices used across a number of fields. In a typical and basic system, a minimum of two different sources of pressure are required (Badawy, 2010). One is related to the actuation of on- chip valves that mainly need level of pressure that is more than 10 psi. The other is known to be driving reagents within the channels of microfluidic. In the traditional sense, the achievement of this is done by the use of two regulators of pressure that are in connection with the tank of compressed gas. However, the nature as well as sizes for all of components is known to be making them unstable for the establishment of system that can be handheld (Bruus, 2008). Even though there is a possibility for using two pumps of miniaturized diaphragm for the establishment of such a system, the considerable fluctuations related to the output pressure over a pump of diaphragm helps in limiting the application. For the enabling of automation and enhanced control, there has been development of handheld handling system for the microfluidic liquid. This system helps in providing two different sources of pressure along with an array of eight lines of pneumatic control for the operation of lab- on- a- chip system (Chen, 2011). One of the sources of pressure is set more the 10 psi with the maximum level of 20 psi for the operation of elastomeric valves on chip, while the other is known to be set below 5 psi for driving the flow of liquid.